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Delivery was fast.Prices were very competitive.
Utilisation : Ce produit est destiné uniquement à la recherche.
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Pureté de 99 % garantie
Usage de recherche uniquement
Paiement sécurisé
Letrozole (1mg/capsule), 60 Capsules
Letrozole is a third-generation non-steroidal aromatase inhibitor that selectively targets CYP19A1 (aromatase), a cytochrome P450 enzyme responsible for catalyzing key steps in estrogen biosynthesis pathways.
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-25% sur tout – jusqu’au 31 octobre
25% sur les prix habituels, en remplacement des autres soldes. Cumulable uniquement avec la remise crypto.
Livraison
Expédition le jour même pour les commandes aux États-Unis passées avant 12 h EST.
Voir la politique de livraison →Testé en laboratoire
Chaque lot est testé pour sa pureté, sa puissance et sa qualité.
Voir les résultats d’analyse →Letrozole is a third-generation non-steroidal aromatase inhibitor that selectively targets CYP19A1 (aromatase), a cytochrome P450 enzyme responsible for catalyzing key steps in estrogen biosynthesis pathways.
By inhibiting aromatase activity, letrozole serves as a valuable research tool for investigating enzyme kinetics, substrate-enzyme interactions, steroidogenic pathway regulation, and feedback mechanisms associated with hormone biosynthesis networks.
Experimental studies have examined its effects on CYP19A1-mediated catalytic processes, transcriptional regulation of steroidogenic pathways, and interactions within endocrine signaling systems. Research applications include aromatase enzyme pharmacology, estrogen biosynthesis pathway investigation, steroidogenic enzyme research, and comparative studies of aromatase inhibitor pharmacology.
- High Purity – 99% Purity Guaranteed
- Independently Lab Tested
- Research Grade Quality
- For Laboratory Research Use Only
3D Molecular Structure
Drag to rotate · scroll to zoom| Chemical Formula | C17H11N5 |
|---|---|
| Synonyms | Femara (trade name), CGS 20267, 4,4'-[(1H-1,2,4-triazol-1-yl)methylene]dibenzonitrile |
| Molar Mass | 285.31 g/mol |
| CAS Number | 112809-51-5 |
| PubChem CID | 3902 |
| Total Compound Content | 60 mg (1 mg per capsule) |
| Shelf Life | 36 months |
Letrozole is a triazole-class, third-generation non-steroidal aromatase inhibitor that selectively targets CYP19A1 (aromatase) through coordination of its triazole nitrogen with the enzyme's haem iron center. This interaction inhibits the catalytic activity of aromatase, making letrozole a valuable research tool for investigating enzyme kinetics, substrate-enzyme interactions, steroidogenic pathway regulation, and cytochrome P450-mediated catalytic mechanisms. Experimental studies have examined its effects on aromatase-associated signaling pathways, transcriptional regulation of steroidogenic enzymes, and molecular processes governing hormone biosynthesis networks. Research applications include aromatase enzyme pharmacology, CYP19A1 inhibition studies, steroidogenic pathway investigation, enzyme-selectivity research, and comparative analysis of aromatase inhibitor pharmacology. Supplied in 1 mg capsules. Independently third-party HPLC-tested; COA available per batch.
Results refer to the tested sample. Check the batch and date in the report.
How does letrozole's mechanism of aromatase inhibition differ from steroidal aromatase inhibitors?
Letrozole is a non-steroidal aromatase inhibitor that interacts reversibly with CYP19A1 through coordination of its triazole nitrogen with the enzyme's haem iron center. Steroidal aromatase inhibitors utilize a different structural framework and interact with the enzyme through distinct molecular mechanisms.
These differences make letrozole a valuable research tool for comparative investigations of aromatase inhibition, enzyme-ligand interactions, active-site binding characteristics, and CYP19A1 pharmacology.
What makes letrozole useful for aromatase pathway research?
Letrozole is a highly selective CYP19A1 inhibitor widely used to investigate aromatase-mediated catalytic processes, steroidogenic pathway regulation, enzyme kinetics, and substrate-enzyme interactions. Experimental studies employ letrozole to examine the role of aromatase within hormone biosynthesis networks, transcriptional regulation of steroidogenic pathways, and the molecular consequences of selective CYP19A1 inhibition.
What is the potency of letrozole in aromatase enzyme studies?
Letrozole demonstrates high affinity for CYP19A1 and exhibits potent inhibition of aromatase activity in experimental systems. Its well-characterized interaction with the aromatase active site has established it as a reference compound for studies of enzyme inhibition, concentration-response relationships, inhibitor selectivity, and comparative aromatase pharmacology.
These characteristics make letrozole a valuable tool for mechanistic investigations of CYP19A1 function and regulation.
Customer Reviews (11)
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Verified Buyer
I am very impressed. Love it.
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Verified Buyer
Good product, fast shipping, will purchase again
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Verified Buyer
The items were very carefully packaged and neatly arranged. Will be buying from
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Verified Buyer
Cannot recommend enough the service. In addition, happy with the quality of this compound. We got fantastic research results. Will buy again.
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Verified Buyer
So happy with the customer service and the compound is pure and high quality. Highly consistent test results. Highly satisfy and will return.
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Verified Buyer
Very happy with the prompt communication, quality is stellar. Five stars all around. The experimental results were exceptional.
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Verified Buyer
The research results have been great so far. Great experience with the support team and it's an exceptionally pure batch. Will purchase again soon.
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Verified Buyer
Exceptional service on the super fast shipping, quality was great and dispatch was incredibly fast. We got fantastic research results. Five stars all around.
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Verified Buyer
The experimental results were exceptional. Great experience with the secure packaging and the chemical quality is top notch. Excellent all-round service.
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Verified Buyer
Top-notch quality from the support team and the quality is absolutely top-tier. Our research results are completely exceeding expectations. Thanks for the outstanding support!
